Powerhouse ingredients for
game-changing benefits.

Present in

The Science

7,8-Dihydroxyflavone (7,8-DHF) mimics Brain-Derived Neurotrophic Factor (BDNF), supporting neuroplasticity—the process that promotes the growth and repair of neural connections essential for learning, memory, and cognitive flexibility. Its small molecular size allows it to easily cross the blood-brain barrier, working within the central nervous system to enhance mental adaptability and emotional resilience.

Present in

The Science

Our extract is standardized to a minimum of 20% bacosides, the active compounds known to support neurotransmitter activity, synaptic plasticity, and antioxidant defense in the brain. Clinically studied for its role in improving memory, cognitive performance, and mood, Bacopa Extract provides a well-rounded approach to brain health and healthy aging.

Present in

The Science

Everyday factors such as diet, lifestyle, and environmental exposures can contribute to oxidative stress, which impacts cognitive function over time. Sulforaphane has been studied for its ability to support the body’s defense against oxidative stress, in part by activating the NRF2 pathway—a critical regulator of cellular protection, antioxidant response, and detoxification. Glucoraphanin, the compound in broccoli seed, supports the body’s natural antioxidant defenses and helps promote phase II detoxification, a process that eliminates environmental and metabolic byproducts. However, without activation by myrosinase, the conversion to sulforaphane can be inefficient, especially when relying solely on gut bacteria. That’s why we also included mustard seed powder in Neuroprotection.

Present in

The Science

Research shows that caffeine supports cognitive function by improving reaction time, attention, and processing speed, making it a key ingredient for mental performance. It also helps support dopamine and norepinephrine production, neurotransmitters that contribute to motivation and mood. Unlike other stimulants, caffeine provides a fast-acting boost in energy and concentration, making it a powerful tool for enhancing focus and productivity.

Present in

The Science

Research shows that L-Theanine supports cognitive function by improving reaction time, attention, and stress resilience. It also supports neurotransmitters like GABA and dopamine, which play key roles in mood and mental performance. Unlike traditional calming agents, L-Theanine reduces occasional stress while maintaining alertness, making it a powerful ingredient for supporting focus, relaxation, and cognitive balance.

Present in

The Science

In an 8-week randomized, double-blind, placebo-controlled trial, co-supplementation with vitamin D and magnesium in obese women with low serum vitamin D and mild to moderate mood symptoms was associated with greater reductions in self-reported mood issues compared to either nutrient alone. The combination also corresponded with increases in serum brain-derived neurotrophic factor (BDNF) and SIRT1, along with reductions in inflammatory markers such as TNF-α and IL-6. Improvements in anthropometric measures, including weight, BMI, and waist circumference, were also observed. These findings suggest a potential synergistic effect of vitamin D and magnesium on mood-related outcomes and inflammation in populations with low vitamin D status.

Present in

The Science

CoQ10 acts as an antioxidant, protecting mitochondria and is essential for cardiovascular health, cognitive performance, and energy metabolism. CoQ10 is found naturally in the body as well as in fatty fish, whole grains, and meats. CoEnzyme Q10 (CoQ10) is essential for cellular energy production, particularly in the brain, where high energy demand makes neurons more susceptible to oxidative stress.

Present in

The Science

By delivering a concentrated dose of these naturally occurring actives, this specialized extract offers a powerful, targeted approach to stress management, making it an essential cornerstone of our Stress Reset formula.

Present in

The Science

Preclinical and clinical studies suggest that curcumin, the key component in CuminUP60®, may also support the body’s natural antioxidant defenses. CuminUP60® is formulated for enhanced absorption, allowing for more efficient delivery of curcuminoids compared to standard turmeric extracts. This advanced form is designed to help support cellular health, stress resilience, and a balanced mood.

Present in

The Science

Research suggests that CDP Choline enhances dopamine release and receptor density, contributing to improved mental energy, motivation, and reward-driven focus. By promoting brain phospholipid levels, it also helps maintain neuronal membrane integrity, supporting long-term brain health and resilience. Additionally, CDP Choline helps protect against oxidative stress, supports brain cell health, and helps sustain mental endurance. With its ability to boost both focus and motivation, CDP Choline is a powerful ingredient for enhancing cognitive performance, attention, and sustained mental energy.

Present in

The Science

Preclinical research confirms that Dihydrohonokiol-B (DHH-B), a compound derived from magnolia bark, may help promote calm behavior in animals under stress. In behavioral studies, mice given DHH-B spent more time in open spaces and displayed reduced stress-related avoidance—effects similar to those seen with low-dose diazepam. Biochemical tests showed that DHH-B supports GABA receptor activity, a key pathway in the body’s natural stress response. These findings suggest that DHH-B may help support relaxation and emotional balance by modulating GABA signaling.

Present in

The Science

GinkoSelect® is standardized to contain ≥24.0% ginkgoflavonglucosides and ≥6.0% ginkgolides A, B, and C, key bioactives that promote cerebral blood flow, neurotransmitter balance, and oxidative stress protection. Additionally, it is meticulously purified to contain ≤5.0 ppm total ginkgolic acids, ensuring a highly refined and safe extract. Clinically researched for its role in enhancing memory, attention, and cognitive processing, GinkoSelect® provides a targeted and reliable approach to brain health and longevity.

Present in

The Science

Research suggests that Lion’s Mane enhances focus, supports mental resilience, and helps protect against age-related cognitive decline by targeting oxidative stress and supporting a healthy inflammation response in the brain. With its neuroprotective and adaptogenic properties, Lion’s Mane is a key ingredient for those looking to maintain sharp thinking, mental clarity, and overall brain health.

Present in

The Science

Magnesium is essential for relaxation, stress support, and overall well-being—it helps regulate the nervous system, supports muscle relaxation, and plays a key role in energy production. By using magnesium bisglycinate in our Stress Reset formula, we ensure your body gets the benefits of magnesium without the digestive discomfort some other forms can cause, helping you unwind and recharge.

Present in

The Science

Research suggests that adequate B12 intake enhances mental stamina, focus, and cognitive resilience, making it a critical component for sustained energy, motivation, and peak performance.

Present in

The Science

NALT is a more soluble and easily absorbed form of tyrosine, making it an efficient way to fuel dopamine synthesis and sustain cognitive performance. Research suggests it can enhance motivation, working memory, and mental endurance by optimizing catecholamine levels, helping maintain focus and drive during demanding tasks.

Present in

The Science

Research suggests that Panax Ginseng can improve memory, reaction time, and overall cognitive performance by supporting blood flow to the brain. Additionally, its antioxidant properties help protect against oxidative stress, which is linked to cognitive issues. This makes Panax Ginseng a key ingredient for those seeking sharper focus, mental endurance, and sustained cognitive performance.

Present in

The Science

Dynamine® is a patented, highly purified form of methylliberine, designed for rapid onset and sustained benefits. Research suggests it supports motivation, stress tolerance, and cognitive endurance by influencing dopamine and adenosine signaling, promoting a clean, stimulant-free boost in mental and physical performance.

Present in

The Science

Research suggests that adequate B6 intake supports memory, processing speed, and mental performance, making it a vital component for sustained focus and clarity.

Present in

The Science

As a redox cofactor, PQQ also helps combat oxidative stress, which can impact memory, focus, and overall brain resilience. Naturally found in trace amounts in foods like fermented soy, kiwi, and spinach, NutriPQQ® provides a concentrated and bioavailable source to help maintain cellular vitality and neuroprotection.

Present in

The Science

Clinically studied for its potential to support memory, focus, and overall cognitive performance, NADH is also being explored for its role in maintaining cellular resilience and healthy neurological aging. Our stabilized form of NADH offers a bioavailable source of this essential coenzyme, helping to fuel brain function and support sustained mental energy throughout the day.

Present in

The Science

Salidroside has been studied for its role in modulating the hypothalamic-pituitary-adrenal (HPA) axis, supporting cellular adaptation to stress. It has also been shown to influence mitochondrial function, antioxidant pathways, and key neurotransmitters such as serotonin, dopamine, and norepinephrine, which are involved in mood, cognitive function, and overall mental performance. The precision fermentation process enhances bioavailability, optimizing absorption for effective support of the body's natural stress response and energy metabolism.

Present in

The Science

Zembrin® is a clinically studied, standardized extract with a patented alkaloid profile, ensuring ≥ 60% mesembrenone + mesembrenol, ≤ 20% mesembrine, and ≥ 5% mesembranol. This unique composition optimizes mood support, cognitive performance, and stress regulation while minimizing sedation​.

Present in

The Science

In its chelated form, selenium is bound to amino acids to enhance absorption and bioavailability. This highly bioavailable form supports healthy neurotransmitter activity, cognitive resilience, and overall well-being.

Present in

The Science

Myrosinase enables the rapid and reliable activation of sulforaphane from glucoraphanin, enhancing its bioavailability and impact. This enzymatic activation is critical for harnessing the full potential of broccoli seed extract. Together, these ingredients help maintain healthy NRF2 pathway activity, support glutathione production and mitochondrial function, and strengthen the body’s response to oxidative stress. By promoting these natural processes, mustard seed plays a key role in supporting brain health, antioxidant activity, and detoxification pathways.

Present in

The Science

Research suggests that supporting autophagy and mitochondrial efficiency helps maintain mental clarity and cognitive longevity.

Present in

The Science

TeaCrine® is a clinically studied, patented form of theacrine designed for sustained cognitive and physical performance. Research suggests it enhances motivation, attention, and energy by influencing dopamine and adenosine signaling, offering a smooth, long-lasting boost without tolerance build-up or overstimulation.

Present in

The Science

By utilizing both roots and leaves (other Ashwagandhas use the roots only), Ashwagandha maximizes its phytochemical diversity, providing a richer spectrum of bioactives, including unique withanolides, polyphenols, and flavonoids, enhancing its stress-modulating, sleep-supporting, and immune-boosting properties. This innovative approach also promotes sustainability, reducing plant waste and pollution while delivering clinically backed benefits for mental clarity, energy balance, emotional well-being, and restorative sleep. Shoden® sets a new standard for potency, efficacy, and eco-conscious innovation in adaptogenic supplements.